What Is Arthrosamid®?
Arthrosamid is a next-generation intra-articular hydrogel injection designed to provide long-lasting relief for knee osteoarthritis. It works by cushioning the joint, reducing inflammation-driven pain, and improving mobility—without surgery.
How Arthrosamid® Works
Arthrosamid® contains non-biodegradable polyacrylamide hydrogel (PAAG). After it is injected into the synovial cavity, the hydrogel:
- Integrates gradually with the synovial membrane
- Creates a stable cushioning layer inside the knee
- Reduces joint friction
- Improves shock absorption
- Leads to progressive, sustained pain relief
Because it is non-degradable, the hydrogel remains in the joint and continues working long-term.
Frequently Asked Questions (FAQs)
Who Is Suitable for Arthrosamid®?
Arthrosamid® may be appropriate for adults with:
- Mild to moderate knee osteoarthritis
- Persistent pain despite physiotherapy, exercise, oral medication or traditional steroid/HA injections
- Pain impacting daily activity, walking, or sleep
- A desire to delay or avoid knee replacement surgery
It is not recommended for inflammatory arthritis (e.g., rheumatoid arthritis) or severely advanced “bone-on-bone” cases.
What Happens During the Procedure?
The procedure is completed in a clinic setting:
- The knee is disinfected.
- Local anaesthetic is applied to ensure comfort.
- Ultrasound guidance is essential for precision.
- A single dose of Arthrosamid® is injected into the joint.
Expected time in clinic: 20–30 minutes.
You can walk immediately afterwards.
How Quickly Will I Feel Relief?
- Some patients feel improvement within 2–4 weeks.
- Relief continues to build as the hydrogel integrates with the joint tissue.
- Clinical studies show pain relief can last months to years.
What Results Should I Expect?
Patients typically report:
- Reduced daily pain
- Fewer flare-ups
- Less stiffness
- Improved walking, standing, and activity tolerance
- Enhanced quality of life
- Reduced reliance on pain medication
In many cases, Arthrosamid® can delay the need for knee replacement surgery.
Is Arthrosamid® a Surgical Procedure?
No. It is a non-surgical, minimally invasive injection performed under local anaesthetic.
How Long Does Arthrosamid® Last?
Because the hydrogel is non-degradable, results can be significantly longer-lasting than:
- Steroid injections
- Hyaluronic acid (HA) injections
Studies show sustained effects over several years, though individual results vary.
Can the Injection Be Repeated?
Arthrosamid® is designed as a single-dose treatment, and repeat injections are rarely needed.
Your clinician will assess the need for any further intervention.
What Are the Risks or Side Effects?
Most effects are mild and temporary:
- Localised swelling
- Warmth or tightness
- Temporary post-injection discomfort
Serious side effects (infection, reaction) are rare. Your clinician will discuss risk minimisation and aftercare.
Is Arthrosamid® Clinically Proven?
Yes. Arthrosamid® has undergone:
- Over 20 years of research and development
- Multicentre, peer-reviewed clinical trials
- Regulatory approval across Europe
It is considered safe with a well-established clinical profile.
